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HR+ HER2- Breast Cancer Resource Center

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Patient-reported outcomes (PROs) in patients with ER+, HER2- advanced breast cancer (ABC) treated with imlunestrant, investigator’s choice standard endocrine therapy, or imlunestrant + abemaciclib: Results from the phase III EMBER-3 trial

Last Updated: Wednesday, July 23, 2025

Patient-reported outcomes from the EMBER-3 study demonstrated that patients with ESR1 mutations experienced better global health status/quality of life and physical functioning with imlunestrant compared to standard of care, which was consistent with the study’s efficacy results.

Journal of Clinical Oncology
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