From the publishers of JADPRO

HR+ HER2- Breast Cancer Resource Center

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Efficacy and safety of CDK4/6 inhibitors: A focus on HR+/HER2- early breast cancer

Last Updated: Friday, February 7, 2025

In a clinical review, researchers evaluated recent data—including data from the NATALEE and monarchE trials—on CDK4/6 inhibition in early-stage HR+ HER2- breast cancer. The review compares differences in patient selection, treatment duration, endocrine backbone therapy, and other study details among these recently published studies.

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