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Fast Facts #5: CRS/Neurotoxicity
Last Updated: Wednesday, October 13, 2021
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News & Literature Highlights
Blood Advances
Local radiation enhances systemic CAR T cell efficacy by augmenting antigen cross-presentation and T-cell infiltration
Blood Advances
Feasibility and favorable responses following investigational CAR T-Cell therapy for relapsed and refractory infant ALL
Bone Marrow Transplantation
Role of bridging RT in relapsed/refractory diffuse large B-cell lymphoma undergoing CAR-T therapy: A multicenter study
Frontiers in Immunology
Chimeric antigen receptor T-cell therapy in relapsed or refractory mantle cell lymphoma: A systematic review and meta-analysis
Blood Advances
Absolute lymphocyte count after BCMA CAR-T therapy is a predictor of response and outcomes in relapsed multiple myeloma
Annals of Medicine
Comprehensive analysis of the efficacy and safety of CAR T-cell therapy in patients with relapsed or refractory B-cell acute lymphoblastic leukemia: A systematic review and meta-analysis
Hematology
Successful treatment of two cases with Philadelphia-chromosome positive acute lymphoblastic leukemia who relapsed after allogeneic stem cell transplantation and the treatments with novel immunotherapies and ponatinib
Hematology
Procalcitonin level threshold and antibiotic use in patients receiving chimeric antigen receptor T-cell therapy
Blood
CAR T cells vs bispecific antibody as third- or later-line large B-cell lymphoma therapy: A meta-analysis
Blood
Optimizing the post-CAR T monitoring period for axicabtagene ciloleucel, tisagenlecleucel, and lisocabtagene maraleucel
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Case Studies
Transverse Myelitis With Paraplegia: An Atypical Manifestation of Neurotoxicity Following CAR T-Cell Therapy
CAR T-cell Infusion in an Outpatient Setting: An Ideal Option for Selected Patients When Available
B-Cell Aplasia, Hypogammaglobulinemia Can Result in Serious, Life-Threatening Infections
Fast Facts
Fast Facts #12: BCMA Targets
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Quizzes
Test your knowledge of atypical manifestation of neurotoxicity following CAR T-cell therapy
Test your knowledge of CAR T-cell therapy
Test your knowledge of CAR T-cell infusion in an outpatient setting