Relapsed/refractory multiple myeloma: A review of available therapies and clinical scenarios encountered in myeloma relapse

This review of available therapies in relapsed/refractory multiple myeloma looks at the pharmacologic mechanisms underlying active therapies such as immunomodulatory agents, proteasome inhibitors, monoclonal antibodies, traditional chemotherapy, and Venetoclax. Researchers also reviewed the clinical data supporting the use of these therapies, organized based on drug resistance/refractoriness, and the role of autologous stem cell transplant.