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Multiple Myeloma Resource Center

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Expert perspectives on current challenges and emerging approaches for multiple myeloma: Narrative review of an inaugural bridging the gaps in leukemia, lymphoma, and multiple myeloma

Last Updated: Thursday, April 10, 2025

A panel of experts discussed the increasingly complex management of multiple myeloma (MM), focusing on controversies in treatment sequencing and selection. Key topics included smoldering MM, transplant eligibility, risk assessment, MRD, relapse management, and novel therapies. Many controversies remain regarding risk assessment, treatment selection, and optimal use of therapies, necessitating further research for improved and more efficacious treatments.

Clinical Lymphoma, Myeloma & Leukemia
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News & Literature Highlights

Nature Cancer

ISB 2001 trispecific T cell engager shows strong tumor cytotoxicity and overcomes immune escape mechanisms of multiple myeloma cells

ASCO 2025

DREAMM-8 study of belantamab mafodotin plus pomalidomide and dexamethasone vs pomalidomide plus bortezomib and dexamethasone in relapsed/refractory multiple myeloma: A subgroup analysis in patients with high-risk cytogenetic features

Blood

Are we ready for an MRD-driven approach in multiple myeloma?

Frontiers in Oncology

Subcutaneous administration of isatuximab in patients with multiple myeloma by an on-body delivery system: Results of a nurse survey

The New England Journal of Medicine

Daratumumab or active monitoring for high-risk smoldering multiple myeloma

Journal of Clinical Oncology

Isatuximab subcutaneous by on-body delivery system vs isatuximab intravenous plus pomalidomide and dexamethasone in relapsed/refractory multiple myeloma: Phase 3 IRAKLIA study

Blood and Lymphatic Cancer

An updated indirect comparison of elranatamab versus a real-world external control arm in triple-class refractory multiple myeloma

Current Obesity Reports

Unraveling obesity and multiple myeloma: Insights from epidemiology and molecular mechanisms

Blood Cancer Journal

Outcomes of elderly patients with relapsed refractory multiple myeloma (RRMM) treated with teclistamab: A multicenter study from the U.S. Multiple Myeloma Immunotherapy Consortium

Bone Marrow Transplantation

Attitudes and perspectives of oncologists about measurable residual disease testing in multiple myeloma: Initiative for standardizing guidelines

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