Recommendations for Screening, Monitoring, Prevention, and Prophylaxis of Infections in Adult and Pediatric Patients Receiving CAR T-Cell Therapy: A Position Paper

This article reviews the incidence, risk factors, and management of infections in adult and pediatric patients receiving CAR T-cell treatment. It provides recommendations in the areas of monitoring and treatment of hypogammaglobulinemia, prevention, prophylaxis, and management of bacterial, viral, and fungal infections, as well as vaccination prior and post CAR T-cell therapy.