Analysis of antibiotic exposure and development of acute graft-vs-host disease following allogeneic hematopoietic cell transplantation
Last Updated: Monday, July 17, 2023
According to data from a single-institution study of patients who underwent allo-HCT, antibiotic choices and schedules during the first few weeks after transplantation were associated with acute GVHD rates. Increased risk of acute GVHD was consistently associated with exposure to carbapenems during weeks 1 and 2 post–allo-HCT (minimum HR among models, 2.75; 95% CI: 1.77-4.28) and exposure to
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