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Multiple Myeloma Resource Center

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The impact of outpatient versus inpatient administration of CAR-T therapies on clinical, economic, and humanistic outcomes in patients with hematological cancer: A systematic literature review

Last Updated: Friday, March 29, 2024

Researchers compared the clinical and economic outcomes associated with the administration of chimeric antigen receptor (CAR)-T cell therapies in both the inpatient and outpatient setting for patients with hematological cancer. Existing evidence was summarized and the hypothesis that outpatient administration of CAR-T therapies yields comparable clinical effectiveness as inpatient treatment while offering significant cost reduction and lower humanistic burden was tested.

Cancers (Basel)
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News & Literature Highlights

Nature Cancer

ISB 2001 trispecific T cell engager shows strong tumor cytotoxicity and overcomes immune escape mechanisms of multiple myeloma cells

ASCO 2025

DREAMM-8 study of belantamab mafodotin plus pomalidomide and dexamethasone vs pomalidomide plus bortezomib and dexamethasone in relapsed/refractory multiple myeloma: A subgroup analysis in patients with high-risk cytogenetic features

Blood

Are we ready for an MRD-driven approach in multiple myeloma?

Frontiers in Oncology

Subcutaneous administration of isatuximab in patients with multiple myeloma by an on-body delivery system: Results of a nurse survey

The New England Journal of Medicine

Daratumumab or active monitoring for high-risk smoldering multiple myeloma

Journal of Clinical Oncology

Isatuximab subcutaneous by on-body delivery system vs isatuximab intravenous plus pomalidomide and dexamethasone in relapsed/refractory multiple myeloma: Phase 3 IRAKLIA study

Blood and Lymphatic Cancer

An updated indirect comparison of elranatamab versus a real-world external control arm in triple-class refractory multiple myeloma

Current Obesity Reports

Unraveling obesity and multiple myeloma: Insights from epidemiology and molecular mechanisms

Blood Cancer Journal

Outcomes of elderly patients with relapsed refractory multiple myeloma (RRMM) treated with teclistamab: A multicenter study from the U.S. Multiple Myeloma Immunotherapy Consortium

Bone Marrow Transplantation

Attitudes and perspectives of oncologists about measurable residual disease testing in multiple myeloma: Initiative for standardizing guidelines

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