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Multiple Myeloma Resource Center

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Teclistamab dosing in responders: Modeling and simulation results from the MajesTEC-1 study in relapsed/refractory multiple myeloma

Last Updated: Wednesday, May 21, 2025

This journal article reports on teclistamab dosing for relapsed/refractory multiple myeloma based on MajesTEC-1 modeling. It supports switching responders to 1.5 mg/kg every other week, demonstrating maintained efficacy. Modeling also suggests 3 mg/kg every four weeks may offer comparable response maintenance, which is being evaluated in ongoing phase III studies.

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