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Multiple Myeloma Resource Center

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Safety and activity of talquetamab in patients with relapsed or refractory multiple myeloma (MonumenTAL-1): A multicentre, open-label, phase 1-2 study

Last Updated: Monday, March 24, 2025

Talquetamab, a GPRC5D-targeted bispecific antibody, has shown high overall response rates in heavily pretreated patients with relapsed or refractory multiple myeloma (RRMM). The MonumenTAL-1 study demonstrated promising activity even in patients who had received previous T-cell redirection therapy.

The Lancet Haematology
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