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Multiple Myeloma Resource Center

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Outcomes of elderly patients with relapsed refractory multiple myeloma (RRMM) treated with teclistamab: A multicenter study from the U.S. Multiple Myeloma Immunotherapy Consortium

Last Updated: Wednesday, May 21, 2025

Researchers found that real-world data shows teclistamab is safe and effective for older RRMM patients (≥75). Safety outcomes (CRS/ICANS) and efficacy (ORR/PFS) were comparable to younger patients and pivotal trials. Advanced age alone should not preclude treatment; careful selection based on functional status is key.

Blood Cancer Journal
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