Symptom distress and fear of progression associated with quality of life in multiple myeloma patients receiving treatment

This study assessed symptom distress, functional impairment, fear of progression (FoP), and quality of life (QOL) in 100 multiple myeloma patients. Common issues included fatigue and pain, with 32% reporting high FoP. Higher QOL was strongly linked to higher performance status, lower symptom distress, and lower FoP, which explained 78.1% of QOL variance. Performance status was the greatest predictor. Patient-centered care addressing symptoms and supportive care is recommended to improve performance status and QOL. .