Ten years of treatment with ruxolitinib for myelofibrosis: a review of safety

Last Updated: Wednesday, August 2, 2023

This review article highlights the safety profile of ruxolitinib in patients with myelofibrosis, specifically in the COMFORT trials leading to its approval and subsequent trials, pooled analyses, and in postmarketing analyses during the 10 years after approval. The authors also discuss common hematologic and nonhematologic adverse events, as well as management strategies and practical considerations.

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Current Hematologic Malignancy Reports

Myeloproliferative neoplasms in children, adolescents, and young adults

British Journal of Haematology

‘MPN Genomic Calculator’: real‐life use in a young population with essential thrombocythaemia

Leukemia

Significant association of cutaneous adverse events with hydroxyurea: results from a prospective non-interventional study in BCR-ABL1-negative myeloproliferative neoplasms (MPN) - on behalf of the German Study Group-MPN

Thrombosis Research

Patient outcomes in myeloproliferative neoplasm-related thrombosis: Insights from the National Inpatient Sample

British Journal of Haemtology

Real‐world non‐interventional long‐term post‐authorisation safety study of ruxolitinib in myelofibrosis

Cancer Medicine

Depressive symptoms and myeloproliferative neoplasms: Understanding the confounding factor in a complex condition

Cancers

Novel concepts of treatment for patients with myelofibrosis and related neoplasms

Expert Review of Hematology

Developing strategies to reduce the duration of therapy for patients with myeloproliferative neoplasms

European Society for Medical Oncology (ESMO) Congress 2021 Abstract

Final results of a phase II study of tipifarnib in chronic myelomonocytic leukemia (CMML) and other myelodysplastic/myeloproliferative neoplasms (MDS/MPN)

European Society for Medical Oncology (ESMO) Congress 2021 Abstract

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