Study of parsaclisib plus ruxolitinib in myelofibrosis discontinued

Last Updated: Tuesday, April 11, 2023

The phase 3 LIMBER-304 study of parsaclisib plus ruxolitinib in patients with myelofibrosis who had a previous suboptimal response to ruxolitinib alone has been discontinued, after a preplanned interim analysis determined that the trial was not expected to meet its primary endpoint of targeted reduction in spleen volume from baseline to week 24.

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Current Hematologic Malignancy Reports

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