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Ropeginterferon alfa-2b versus standard therapy for polycythaemia vera (PROUD-PV and CONTINUATION-PV): A randomised, non-inferiority, phase 3 trial and its extension study

Last Updated: Tuesday, March 24, 2020

Although ropeginterferon alfa-2b did not demonstrate noninferiority to hydroxyurea at 12 months among patients with early-stage polycythemia vera, results from the phase 3 PROUD-PV trial and its CONTINUATION-PV extension trial showed improved responses to the novel monopegylated interferon at 36 months, in addition to good tolerability.

Lancet Haematology
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