Novel treatment strategies for hormone receptor (HR)-positive, HER2-negative metastatic breast cancer

There is current disagreement on the best treatment plan for patients with HR+ HER2- breast cancer whose disease progresses after receiving combination CDK4/6 inhibitors and endocrine therapy. To help meet this research need, investigators used clinical evidence and genomic profiling to provide new insight into the use of endocrine therapy and other targeted therapies for the treatment of this patient population.