Novel treatment strategies for hormone receptor (HR)-positive, HER2-negative metastatic breast cancer

Last Updated: Thursday, August 1, 2024

There is current disagreement on the best treatment plan for patients with HR+ HER2- breast cancer whose disease progresses after receiving combination CDK4/6 inhibitors and endocrine therapy. To help meet this research need, investigators used clinical evidence and genomic profiling to provide new insight into the use of endocrine therapy and other targeted therapies for the treatment of this patient population.

Journal of Clinical Medicine

Radiographics

Breast cancer surveillance in patients with a personal history of breast cancer: Updates and controversies

Frontiers in Oncology

Real-world effectiveness of CDK4/6i in first-line treatment of HR+/HER2- advanced/metastatic breast cancer: Updated systematic review

Journal of Clinical Oncology

Adjuvant dose-dense chemotherapy in hormone receptor-positive breast cancer

Seminars in Nuclear Medicine

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The Breast

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BMC Women’s Health

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npj Precision Oncology

Successful unconventional precision treatment of inflammatory hormone receptor-positive breast cancer guided by molecular profiling

Cancer Treatment Reviews

First versus second-generation molecular profiling tests: How both can guide decision-making in early-stage hormone-receptor positive breast cancers?

European Journal of Nuclear Medicine and Molecular Imaging

Predictive and prognostic value of 18F-FES PET/CT for patients with recurrent or metastatic breast cancer treated with endocrine therapy plus cyclin-dependent kinase 4/6 inhibitors

Chinese Journal of Cancer Research

Clinicopathological and molecular features of HR + /HER2 - breast cancer patients with distinct endocrine resistance patterns

HR+ HER2- Breast Cancer Resource Center