Dormancy leading to late recurrence in breast cancer: A case of hormone receptor-positive supraclavicular metastasis 10 years after the initial treatment

A 65-year-old woman with a history of stage IIIC invasive ductal carcinoma developed recurrent ER+/PR+/HER2- breast cancer 10 years later. This case study underscores the potential for late recurrence in this breast cancer type, despite aggressive treatment and years of remission. The researchers concluded that clinicians must understand dormancy and reactivation mechanisms and must tailor follow-up strategies and treatment approaches to improve outcomes and quality of life for patients.