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HR+ HER2- Breast Cancer Resource Center

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Clinicopathological and molecular features of HR + /HER2 - breast cancer patients with distinct endocrine resistance patterns

Last Updated: Monday, April 14, 2025

Researchers explored molecular features and therapeutic targets for patients with HR+ HER2- breast cancer who experienced disease recurrence. They found that patients with different relapse patterns presented with unique molecular features in their primary tumors, which can potentially guide targeted therapies.

Chinese Journal of Cancer Research
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Patient-reported outcomes (PROs) in patients with ER+, HER2- advanced breast cancer (ABC) treated with imlunestrant, investigator’s choice standard endocrine therapy, or imlunestrant + abemaciclib: Results from the phase III EMBER-3 trial

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