From the publishers of JADPRO

HR+ HER2- Breast Cancer Resource Center

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Breast cancer surveillance in patients with a personal history of breast cancer: Updates and controversies

Last Updated: Tuesday, June 17, 2025

A review of current screening guidelines for patients who have a personal history of breast cancer. The review highlights the challenges involved in determining when to initiate or discontinue screening mammography, when to perform screening versus diagnostic mammography, and when to perform offline versus live screening. It also gives updates on emergent supplemental imaging modalities and compliance with screening recommendations for patients with a personal history of breast cancer.

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News & Literature Highlights

Journal of Clinical Oncology

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Biomedicines

Real-world analysis of adherence to abemaciclib and endocrine therapy in women with HR+/HER2- breast cancer

Journal of Clinical Oncology

Camizestrant + CDK4/6 inhibitor for the treatment of emergent ESR1 mutations during first-line endocrine-based therapy and ahead of disease progression in patients with HR+/HER2– advanced breast cancer: Phase 3, double-blind ctDNA-guided SERENA-6 trial

Journal of Clinical Oncology

Patient-reported outcomes (PROs) in patients with ER+, HER2- advanced breast cancer (ABC) treated with imlunestrant, investigator’s choice standard endocrine therapy, or imlunestrant + abemaciclib: Results from the phase III EMBER-3 trial

Journal of Clinical Oncology

The TRADE study: A phase 2 trial to assess the tolerability of abemaciclib dose escalation in early-stage HR+/HER2- breast cancer

The Breast

Real-world risk of recurrence and treatment outcomes with adjuvant endocrine therapy in patients with stage II-III HR+/HER2- early breast cancer

Radiographics

Breast cancer surveillance in patients with a personal history of breast cancer: Updates and controversies

Frontiers in Oncology

Real-world effectiveness of CDK4/6i in first-line treatment of HR+/HER2- advanced/metastatic breast cancer: Updated systematic review

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