Organ-specific response after low-dose interleukin-2 therapy for steroid-refractory chronic graft-versus-host disease

Last Updated: Wednesday, September 7, 2022

An analysis of 105 patients enrolled in five clinical trials low-dose interleukin-2 therapy for steroid-refractory chronic GvHD, found the overall response rate after eight or 12 weeks was 48.6% and 53.3% with continued therapy. The organ-specific response rate was highest in liver and lowest in the lung.

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Organ-specific response after low-dose interleukin-2 therapy for steroid-refractory chronic graft-versus-host disease

Targeted Oncology

Acute GVHD responds quickly to itolizumab treatment in phase 1b trial

Pediatric Blood & Cancer

Prophylactic donor lymphocyte infusion after haploidentical hematopoietic cell transplantation and post-transplant cyclophosphamide for treatment of high-risk myeloid neoplasms in children: A retrospective study

Bone Marrow Transplantation

Acute GVHD classification based on the dynamics of GVHD skin involvement from its appearance to the start of systemic treatment

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FDA guidance explores trial design, supporting data for GVHD treatments

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