Hospital survival following pediatric HSCT: changes in complications, ICU therapies and outcomes over 10 years

Last Updated: Thursday, December 14, 2023

Data from a database analysis of pediatric patients who underwent hematopoietic stem cell transplantation (HSCT) showed that, although hospital survival for HSCT improved from 2009 to 2018, GVHD is a factor associated with decreased survival (p = 0.02), along with allogeneic HSCT (p < 0.01), infection (p < 0.01), and ICU therapies (p < 0.01). GVHD occurred in 33% of patients who underwent allogeneic HSCT.

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Pediatric Blood & Cancer

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Bone Marrow Transplantation

Acute GVHD classification based on the dynamics of GVHD skin involvement from its appearance to the start of systemic treatment

Regulatory Focus

FDA guidance explores trial design, supporting data for GVHD treatments

Targeted Oncology

Acute GVHD responds quickly to itolizumab treatment in phase 1b trial

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