Desiccating Stress Significantly Increases the Risk for Chronic Ocular Graft-versus-Host-Disease

Last Updated: Tuesday, October 4, 2022

Researchers found that 73% of patients who were exposed to desiccating-stress developed ocular GvHD compared to 30% who were transplanted under high humidity conditions. This suggests that adjusting air humidity could have the potential to reduce the rate of ocular GvHD.

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Pediatric Blood & Cancer

Prophylactic donor lymphocyte infusion after haploidentical hematopoietic cell transplantation and post-transplant cyclophosphamide for treatment of high-risk myeloid neoplasms in children: A retrospective study

Bone Marrow Transplantation

Acute GVHD classification based on the dynamics of GVHD skin involvement from its appearance to the start of systemic treatment

Regulatory Focus

FDA guidance explores trial design, supporting data for GVHD treatments

Targeted Oncology

Acute GVHD responds quickly to itolizumab treatment in phase 1b trial

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Healthcare resource utilization and costs of steroid-associated complications in patients with graft-versus-host disease

Journal of Clinical Oncology

Naive T-cell depletion to prevent chronic graft-versus-host disease

Blood

A phase 1 study of donor regulatory T-cell infusion plus low-dose interleukin-2 for steroid-refractory chronic graft-vs-host disease

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Abatacept for prophylaxis of acute graft-vs-host disease

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