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Graft-vs.-Host Disease Resource Center

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A Multiparameter Prognostic Risk Score of Chronic GVHD based on CXCL10 and Plasmacytoid DC (pDC) levels in the Peripheral Blood at 3 months after Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)

Last Updated: Friday, March 10, 2023

Looking for predictive biomarkers in chronic GVHD, a retrospective study found that a multiparameter score that includes a history of previous acute GVHD, concentration of CXCL10 and the number of plasmacytoid dendritic cell (pDC) levels in the peripheral blood at three months after alloHCT may identify patients at different risk of cGVHD. Validation in a larger cohort is still required.  

Transplantation and Cellular Therapy
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