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Multiple Myeloma Resource Center

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SLiM CRAB criteria revisited: temporal trends in prognosis of patients with smoldering multiple myeloma who meet the definition of ‘biomarker-defined early multiple myeloma’—a systematic review with meta-analysis

Last Updated: Wednesday, June 14, 2023

This systematic review examined whether the risk of progression of patients with SLiM CRAB MM (biomarker-defined patients with smoldering multiple myeloma with ≥60% bone marrow plasma cells, free light chain ratio ≥100, and >1 MRI-defined ≥5 mm focal lesion) to CRAB positive MM described in recent studies differs from that reported in earlier studies published before the introduction of the new diagnostic criteria.

The Lancet
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