Depressive symptoms and myeloproliferative neoplasms: Understanding the confounding factor in a complex condition

Based on data from an international survey of patients with myeloproliferative neoplasms, almost one in four exhibited depressive symptoms. Additionally, patients who reported worse depressive symptoms also scored significantly higher on the Myeloproliferative Neoplasm Symptom Assessment Form (mean 40.8 vs 24.6; P <.001), had higher worst fatigue score (mean 7.8 vs 5.8; P <.001), and had worse overall quality of life (mean 5.7 vs 3.1; P <.0001).