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Metastatic Triple-Negative Breast Cancer Resource Center

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Pembrolizumab Plus Chemotherapy in Advanced Triple-Negative Breast Cancer

Last Updated: Wednesday, August 3, 2022

In an interim analysis of the phase 3 KEYNOTE-355 trial, the addition of pembrolizumab to chemotherapy resulted in longer progression-free survival than chemotherapy alone among patients with advanced triple-negative breast cancer whose tumors expressed PD-L1 with a combined positive score of 10 or more. The results of the final analysis of overall survival have not been reported.

New England Journal of Medicine
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