From the publishers of JADPRO

Metastatic HER2-Positive Breast Cancer Resource Center

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Final overall survival (OS) for abemaciclib plus trastuzumab +/- fulvestrant versus trastuzumab plus chemotherapy in patients with HR+, HER2+ advanced breast cancer (monarcHER): A randomized, open-label, phase II trial

Last Updated: Wednesday, December 14, 2022

Data from the phase 2 monarcHER trial—presented during the 2022 ESMO Congress—show that abemaciclib plus trastuzumab with or without fulvestrant improved median overall survival, compared with chemotherapy plus trastuzumab, in patients with HR+, HER2+ advanced breast cancer.

ESMO Congress 2022 Abstract
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ESMO Congress 2022 Abstract

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