Clinical safety and pharmacokinetics (PK) data of DZD1516, an BBB-penetrant selective HER2 inhibitor for the treatment of HER2-positive metastatic breast cancer
Last Updated: Wednesday, December 14, 2022
According to data from a phase 1 trial presented during the 2022 ESMO Congress, HER2 tyrosine kinase inhibitor DZD1516 is able to fully penetrate the blood-brain barrier and is well tolerated at doses ≤ 250 mg twice daily among patients with HER2+ metastatic breast cancer.
Advertisement
News & Literature Highlights