From the publishers of JADPRO

Gastrointestinal Stromal Tumor Resource Center

Advertisement

Nanotechnology in imatinib delivery: Advancing cancer treatment through innovative nanoparticles

Last Updated: Monday, March 24, 2025

Nanotechnology offers promising approaches to enhance the delivery of Imatinib, a key drug for GIST, by improving its solubility, stability, and targeted distribution. These methods, including polymeric and lipid-based nanoparticles, aim to overcome imatinib's limitations and even facilitate co-delivery with other anticancer drugs. Addressing scalability and regulatory hurdles is crucial for translating this potential into standard GIST treatment.

Medical Oncology
Advertisement
News & Literature Highlights

Clinical Cancer Research

Phase 2 trial of ponatinib in patients with metastatic gastrointestinal stromal tumor following failure or intolerance of prior therapy with imatinib (POETIG trial)

Oncology Letters

Prolonged survival of a case with three different malignancies - cutaneous malignant melanoma, gastrointestinal stromal tumor and thyroid papillary cancer: A case report

Pharmaceutics

Tyrosine kinase inhibitors for gastrointestinal stromal tumor after imatinib resistance

Clinical Cancer Research

Circulating tumor DNA as a molecular biomarker in the phase II trial of imatinib plus binimetinib in patients with advanced gastrointestinal stromal tumors

Gastric Cancer

Evaluating boron neutron capture therapy as a potential treatment for unresectable gastrointestinal stromal tumors

Autophagy

Excessive autophagic degradation of MYLK3 causes sunitinib-induced cardiotoxicity

Hematology/Oncology Clinics of North America

Gastrointestinal stromal tumor: Current approaches and future directions in the treatment of advanced disease

Oncologist

The management of imatinib-associated severe skin rash in gastrointestinal stromal tumor: Desensitization therapy and pharmacogenetic investigation

Cancers

Multifocal gastrointestinal stromal tumors (GISTs) of the small intestine in patients with neurofibromatosis type 1 (NF-1): Meta-analysis and systematic review of the literature

Healthcare

The many faces of intestinal tumors in adults, including the primary role of CT imaging in emergencies and the important role of cross-sectional imaging: A pictorial review

Advertisement
Advertisement