From the publishers of JADPRO

Gastrointestinal Stromal Tumor Resource Center

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Nanotechnology in imatinib delivery: Advancing cancer treatment through innovative nanoparticles

Last Updated: Monday, March 24, 2025

Nanotechnology offers promising approaches to enhance the delivery of Imatinib, a key drug for GIST, by improving its solubility, stability, and targeted distribution. These methods, including polymeric and lipid-based nanoparticles, aim to overcome imatinib's limitations and even facilitate co-delivery with other anticancer drugs. Addressing scalability and regulatory hurdles is crucial for translating this potential into standard GIST treatment.

Medical Oncology
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News & Literature Highlights

Surgical Case Reports

Neoadjuvant chemotherapy followed by laparoscopic and endoscopic cooperative surgery for locally advanced duodenal gastrointestinal stromal tumor: A case report

Journal of the College of Physicians and Surgeons—Pakistan

Predictive significance of changes in haemoglobin level following imatinib treatment in patients with advanced gastrointestinal stromal tumour

European Journal of Clinical Pharmacology

Influence of genetic variants of imatinib on pharmacokinetics and recurrence-free survival in postoperative patients with gastrointestinal stromal tumor

Pathology, Research and Practice

An interpretable machine learning framework for automated mitosis detection in gastrointestinal stromal tumors

Molecular Therapy Oncology

Targeting MITF as a tyrosine-kinase-inhibitor-independent strategy for treating GIST

Radiology Case Reports

Gastrointestinal stromal tumor of the rectum: A case report with emphasis on MRI-pathologic correlation

World Journal of Gastrointestinal Oncology

Utility of inflammatory markers as predictors of recurrence in gastrointestinal stromal tumors: Insights from a nomogram-based approach

Surgical Endoscopy

A novel prognostic system for locally advanced gastrointestinal stromal tumors after neoadjuvant imatinib therapy based on the metro-ticket paradigm: a retrospective dual-center study

Langenbeck's Archives of Surgery

Partial resection of rectum for rectal GIST by posterior approach

Clinical and Translational Medicine

Beta-elemene promotes ferroptosis to improve the sensitivity of imatinib in gastrointestinal stromal tumours by targeting N6AMT1

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