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Gastrointestinal Stromal Tumor Resource Center

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Gastrointestinal stromal tumor of the rectum: A case report with emphasis on MRI-pathologic correlation

Last Updated: Wednesday, October 1, 2025

The source is a case report published in Radiology Case Reports detailing the diagnosis and management of a gastrointestinal stromal tumor (GIST) in the rectum of a 73-year-old male presenting with incomplete defecation. The report emphasizes the MRI and pathological correlation, noting the tumor's characteristic features such as homogeneous signals on MRI and DOG-1 positivity confirmed by immunohistochemistry. Following the complete surgical resection of the mass, the patient's symptoms resolved, which reinforces the importance of early diagnosis for this rare rectal malignancy. The discussion also differentiates rectal GISTs from other tumors like leiomyomas and adenocarcinomas based on specific imaging and pathological markers.

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