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Treatment-specific risk of subsequent malignant neoplasms in five-year survivors of diffuse large B-cell lymphoma

Last Updated: Wednesday, March 13, 2024

Results from an analysis of the long-term risk of subsequent malignant neoplasms (SMNs) among 5-year DLBCL survivors show increased risks for survivors ≤40 years at first treatment and survivors treated with >4500 mg/m2 cyclophosphamide/>300 mg/m2 doxorubicin. Survivors who received rituximab had a lower risk of subdiaphragmatic solid SMNs (HR 0.5, 95% CI 0.3-1.0) compared with those who did not receive rituximab. 

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