Brentuximab vedotin combination for relapsed diffuse large B-cell lymphoma
Last Updated: Friday, February 7, 2025
Data from an interim analysis of the randomized phase 3 ECHELON-3 trial of patients with relapsed or refractory DLBCL found that the addition of brentuximab vedotin to lenalidomide and rituximab improved overall survival. After a median follow-up of 16.4 months, the median overall survival was 13.8 months versus 8.5 months among patients who received placebo, lenalidomide, and rituximab (HR 0.63; 95% CI, 0.45–0.89; two-sided P = .009).
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