Cancer death rate drops by 33%, AACR report shows

Last Updated: Tuesday, October 24, 2023

Although not specific to CLL, the American Association for Cancer Research (AACR) recently released its annual Cancer Progress Report, which revealed that the age-adjusted overall cancer death rate in the United States fell by 33% between 1991 and 2020 - an estimated 3.8 million cancer deaths averted. The decrease was partially attributed to the significant number of immunotherapy approvals over the past several years, as well as the more recent CAR T-cell therapy approvals.

AACR press release

British Journal of Hematology

Repeated COVID-19 vaccination to maximum antibody response yields very low mortality and hospitalisation rates in patients with CLL and MBL

Hematological Oncology

Patients' preferences for chronic lymphocytic leukemia treatment: The CHOICE study

Blood Advances

Factors associated with long-term outcomes of CD19 CAR T-cell therapy for relapsed/refractory CLL

2023 Meeting of the Society of Hematologic Oncology (SOHO)

Outcomes of U.S. military veterans with chronic lymphocytic leukemia (CLL) treated with different first-line treatments from 1998 to 2020.

American Journal of Hematology

Orelabrutinib in relapsed or refractory chronic lymphocytic leukemia/small lymphocytic lymphoma patients: Multi-center single-arm, open-label, phase 2 study

FDA.gov

FDA approves zanubrutinib for CLL or SLL

Blood

Efficacy of pirtobrutinib in covalent BTK-inhibitor pre-treated relapsed/refractory CLL/SLL: Additional patients and extended follow-up from the phase 1/2 BRUIN study

European Hematology Association 2022 Congress Abstract

Venetoclax-obinutuzumab for previously untreated chronic lymphocytic leukemia: 5-year results of the randomized CLL14 study

Blood

Updated results from a multicenter, phase 2 study of acalabrutinib, venetoclax, obinutuzumab (AVO) in a population of previously untreated patients with CLL enriched for high-risk disease

Blood

Genetic markers and front line FCR/BR vs. RVe, GVe and GIVe treatment: Outcome results from the CLL13/GAIA trial

Chronic Lymphocytic Leukemia Resource Center

Cancer death rate drops by 33%, AACR report shows

British Journal of Hematology

Repeated COVID-19 vaccination to maximum antibody response yields very low mortality and hospitalisation rates in patients with CLL and MBL

Hematological Oncology

Patients' preferences for chronic lymphocytic leukemia treatment: The CHOICE study

Blood Advances

Factors associated with long-term outcomes of CD19 CAR T-cell therapy for relapsed/refractory CLL

2023 Meeting of the Society of Hematologic Oncology (SOHO)

Outcomes of U.S. military veterans with chronic lymphocytic leukemia (CLL) treated with different first-line treatments from 1998 to 2020.

American Journal of Hematology

Orelabrutinib in relapsed or refractory chronic lymphocytic leukemia/small lymphocytic lymphoma patients: Multi-center single-arm, open-label, phase 2 study

FDA.gov

FDA approves zanubrutinib for CLL or SLL

Blood

Efficacy of pirtobrutinib in covalent BTK-inhibitor pre-treated relapsed/refractory CLL/SLL: Additional patients and extended follow-up from the phase 1/2 BRUIN study

European Hematology Association 2022 Congress Abstract

Venetoclax-obinutuzumab for previously untreated chronic lymphocytic leukemia: 5-year results of the randomized CLL14 study

Blood

Updated results from a multicenter, phase 2 study of acalabrutinib, venetoclax, obinutuzumab (AVO) in a population of previously untreated patients with CLL enriched for high-risk disease

Blood

Genetic markers and front line FCR/BR vs. RVe, GVe and GIVe treatment: Outcome results from the CLL13/GAIA trial

“Double-Refractory” CLL: Progressive Disease after Therapy With Both a BTK Inhibitor and a BCL2 Inhibitor

Management of Atrial Fibrillation in Patients With CLL on BTK Inhibitors

The Importance of Shared Decision-Making in the Frontline Setting