The potential of phytomedicines to optimize CAR-T cell therapy in cancer

CAR T-cell therapy has transformed treatment for hematologic cancers but remains less effective in solid tumors, prompting interest in phytomedicines as potential adjuvants. Certain phytomedicines show promise in modulating the tumor microenvironment and enhancing immune responses, although hurdles persist in their development, and more research is needed to establish their safety and efficacy.