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CAR T-Cell Therapy Resource Center

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“Off-the-Shelf” CAR T-Cell Therapy Tested in Pediatric B-Cell Leukemia

Last Updated: Wednesday, March 22, 2023

Based on previously reported data regarding use of experimental allogeneic gene-edited T cells in place of CAR T cells as therapies for children with recurrent or refractory B-cell acute lymphoblastic leukemia, this phase I clinical trial resulted in remission for four of six children who were infused with allogeneic CAR T cells.

JAMA
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