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Obecabtagene autoleucel in adults with B-cell acute lymphoblastic leukemia

Last Updated: Tuesday, December 9, 2025

Researchers conducted a phase 1b-2 multicenter study of obecabtagene autoleucel (obe-cel) in adults with relapsed or refractory B-cell acute lymphoblastic leukemia (ALL). Obe-cel resulted in a high incidence of durable response among adults with relapsed or refractory B-cell ALL, with a low incidence of grade 3 or higher immune-related toxic effects.  

The New England Journal of Medicine
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