In vivo generation of anti-BCMA CAR-T cells in relapsed or refractory multiple myeloma: A phase 1 study

Last Updated: Monday, June 15, 2026

A phase 1, single-arm, open-label trial evaluated the safety and tolerability of ESO-T01, a nanobody-directed, immune-shielded lentiviral vector, in adults with relapsed or refractory multiple myeloma. The results provided preliminary evidence on the feasibility and safety of this approach, representing a potential area for further study.

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