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CAR T-Cell Therapy Resource Center

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Efficacy, safety and cost-effectiveness of CAR-T therapy

Last Updated: Monday, March 9, 2026

Researchers summarize the latest innovations in CAR T-cell therapy for multiple myeloma, osteosarcoma, glioblastoma, melanoma, and multiple childhood malignancies. They also discuss challenges, including the antigen escape phenomenon, “on-target off-tumor” toxicity, penetration into solid tumor tissue, and financial concerns.

British Journal of Clinical Pharmacology
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