From the publishers of JADPRO

CAR T-Cell Therapy Resource Center

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Current state and perspectives of CAR T-cell therapy in central nervous system diseases

Last Updated: Wednesday, May 14, 2025

A review of the expanding use of B cell–directed CAR T cells in patients with central nervous system diseases, such as neuromyelitis optica spectrum disorder and multiple sclerosis. The researchers also discuss emerging and preclinical data on the potential uses of CAR T-cell therapy in gliomas and neurodegenerative diseases.

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