CAR-T cell therapy in ovarian cancer: Where are we now?

Last Updated: Friday, October 10, 2025

A review of several early-phase clinical trials evaluating CAR T-cell therapies in ovarian cancer. The researchers address ongoing challenges such as cytokine-associated and “on-target, off-tumor” toxicities, as well as common adverse events, including cytokine release syndrome, hemophagocytic lymphohistiocytosis/macrophage activation-like syndrome, and neurotoxicity.

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