TOR1B: a predictor of bone metastasis in breast cancer patients

Using breast cancer gene expression data and clinical information from public databases, researchers found that novel biomarker TOR1B was significantly upregulated in patients with breast cancer with brain metastases (P < 0.05). In multivariate analysis, a low expression level of TOR1B was associated with delayed metastasis to bone in patients with breast cancer (HR, 0.28; 95% CI: 0.094-0.84).