Treatment Outcomes and Safety of Mobocertinib in Platinum-Pretreated Patients With EGFR Exon 20 Insertion–Positive Metastatic Non–Small Cell Lung Cancer

Last Updated: Monday, November 29, 2021

In this open-label, phase 1/2 nonrandomized clinical trial, mobocertinib, an oral tyrosine kinase inhibitor designed to selectively target EGFRex20ins mutations, was associated with clinically meaningful benefit in patients with previously treated EGFRex20ins-positive mNSCLC, with a manageable safety profile.

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