Molecular Testing and Targeted Therapy for Non-Small Cell Lung Cancer: Current Status and Perspectives

Molecular testing has become a mandatory component of NSCLC management. Comprehensive NSCLC testing for multiple predictive markers requires the analysis of distinct biological molecules (DNA, RNA, proteins) and, therefore, the involvement of different analytical platforms (PCR, DNA sequencing, immunohistochemistry, FISH). There are ongoing efforts aimed at the integration of multiple NSCLC molecular assays into a single diagnostic pipeline.