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Biomarkers in NSCLC Resource Center

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Cardiac Safety of Osimertinib: A Review of Data

Last Updated: Wednesday, January 20, 2021

Osimertinib is a third-generation, CNS-active, irreversible, oral epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) that potently and selectively inhibits both EGFR-TKI-sensitizing and T790M resistance mutations. The authors assessed the cardiac failure risk in patients receiving osimertinib by evaluating the available data.

Journal of Clinical Oncology
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