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What about the heart–pediatric ALL survivors show cardiopulmonary limitations in the MinimALL Study

Last Updated: Tuesday, July 1, 2025

The MinimALL study investigated cardiopulmonary limitations in pediatric cancer survivors (PCS), specifically those who had acute lymphoblastic leukemia or Hodgkin disease. Researchers used cardiopulmonary exercise testing and echocardiography with strain imaging to assess fitness and cardiac function. Findings indicate reduced exercise capacity and early diastolic dysfunction in PCS, with detraining suggested as a contributing factor to diminished peak oxygen uptake.

European Journal of Pediatrics
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