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Acute Lymphoblastic Leukemia Resource Center

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Vincristine/volasertib polymersome injection enables high-efficiency synergistic treatment of acute lymphoblastic leukemia

Last Updated: Wednesday, May 28, 2025

In this report, a vincristine/volasertib polymersome (Ps-VCR/Vol) nanocombo is presented for synergistic high-efficacy ALL treatment. This nanocombo demonstrated strong synergy (3.3-6.8-fold) and enhanced anti-ALL activity in cells and mouse models, effectively inhibiting leukemia progression and prolonging survival without inducing toxicity. 

Acta Biomaterialia
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