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Acute Lymphoblastic Leukemia Resource Center

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Sarcopenia in children with acute leukemia worsened after induction therapy

Last Updated: Wednesday, May 28, 2025

This study evaluated muscle mass in pediatric leukemia patients using CT. Skeletal muscle mass significantly decreased after induction therapy. This loss significantly correlated with pre-treatment IGF-1 levels, meaning it was more severe in patients with higher pre-treatment IGF-1. 

Endocrine Journal
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