A rare case study of granular acute lymphoblastic leukemia combined with pleural infiltration

In this case study, granular acute lymphoblastic leukemia is presented as a rare B-ALL subtype characterized by abundant coarse granules in blasts, which can morphologically resemble other conditions. Comprehensive diagnostic workups, including cytochemical and immunophenotypic analyses, are essential to avoid misdiagnosis. The reported case was ultimately diagnosed as granular ALL through these methods.